Usa student worker bachelor degree high risk clinical science - united states, cambridge bay
co-op,
cell-based therapy/immuno-oncology
cambridge, ma
we re-engineer immune cells to adaptively transfer to patients to selectively kill the tumor cells. immune cells will function as living drugs and in favorable situations expand and exert a strong anti-tumor response. similarly, they are bound by the same laws that endogenous human cells are, such as exhaustion by tumor-produced factors, abnormal tumor vessels, and other obstacles that a suppressive tumor microenvironment poses. we try to remove barriers to the success of cell-based therapies in our group.
the cell therapy co-op will work hands-on in the lab in developing assays and techniques to mimic the tumor microenvironment and testing antibodies and biomaterials (e.g., nanoparticles) that alter the immune system in favor of tumor cell eradication. as part of a newly established team, the co-op will have the opportunity to make significant contributions to the research and development on a daily basis.
the ability to learn quickly, work on multiple assignments, and effectively document scientific data are key components of the role.
responsibilities:
maintain cancer cell lines in culture, including routine passaging of cells and maintenance of research cell banks
isolate primary immune cells from whole blood or leukopaks
plan and execute in vitro experiments, including (a) test nanoparticle-based formulations in wb or isolated immune cells, (b) analysis using flow cytometry, (c) measure cytokine release using elisa assays
carefully record findings using electronic laboratory notebooks
write sops in full detail to ensure reproducibility of the work
communicate results to team members and participate in meetings
maintain laboratory equipment
perform additional tasks to support research and development as the scope of the job changes as necessitated by growth of the team
skills:
strong technical/analytical skills to identify and solve problems
proven ability to work with a high level of integrity, accuracy, and attention to detail
strong organizational skills in order to maintain a high level of productivity to complete assignments on-time
excellent oral and written communication skills for effectively interfacing with all members of the company
self-motivated, enthusiastic, and results-oriented
job requirements:
pursuing a bs or ms in biology, chemistry, immunology, pharmaceutical sciences, bioengineering, biomaterials, or biochemistry
ability to work hands-on with cells and laboratory equipment
willingness to work with human-derived cells and mouse tissue
equal opportunity employer/veterans/disabled
the company will consider qualified applicants with arrest and conviction records
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